No, the blisters are the body's natural allergic reaction to poison ivy, oak and sumac plants. If the blisters break and ooze, the fluid does not contain the oil that causes spreading.

Oil from the original contact with poison oak and poison ivy will continue spreading (unless removed) for the first one or two days. If new areas of rash appear after three days, you are most likely getting re-exposed to the plant oil from contaminated clothing, tools or even your cat or dog.